Fujino, G., Noguchi, T., Matsuzawa, A., Yamauchi, S., Saitoh, M., Takeda, K. and Ichijo, H.
Thioredoxin and TRAF family proteins regulate ROS-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1.
Mol. Cell. Biol., 27, 8152-8163 (2007).
  Osaka, N., Takahashi, T., Murakami, S., Matsuzawa, A., Noguchi, T., Fujiwara, T., Aburatani, H., Moriyama, K., Takeda, K. and Ichijo, H.
ASK1-dependent recruitment and activation of macrophages induce hair growth in skin wounds.
J. Cell Biol., 176, 903-909 (2007).
Takeda, K., Shimozono, R., Noguchi, T., Umeda, T., Morimoto, Y., Naguro, I., Tobiume, K., Saitoh, M., Matsuzawa, A. and Ichijo, H.
Apoptosis signal-regulating kinase 2 (ASK2) functions as a MAP3K in a heteromeric complex with ASK1.
J. Biol. Chem., 282, 7522-7531 (2007).
Ito, G., Okai, T., Fujino, G., Takeda, K., Ichijo, H., Katada, T. and Iwatsubo, T.
GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial parkinson's disease.
Biochemistry, 46, 1380-1388 (2007).
  Yan, W., Arai, A., Aoki, M., Ichijo, H. and Miura, O.
ASK1 is activated by arsenic trioxide in leukemic cells through accumulation of reactive oxygen species and may play a egative role in induction of apoptosis.
Biochem. Biophys. Res. Commun., 355, 1038-1044 (2007).
  Kuwamura, H., Tominaga, K., Shiota, M., Ashida, R., Nakao, T., Sasaki, E., Watanabe, T., Fujiwara, Y., Oshitani, N., Higuchi, K., Ichijo, H., Arakawa, T. and Iwao, H.
Growth inhibition of colon cancer cells by transfection of dominant-negative apoptosis signal-regulating kinase-1.
Oncol Rep., 2007 17, 781-786 (2007).
  Saito, J., Toriumi, S., Awano, K., Ichijo, H., Sasaki, K., Kobayashi, T. and Tamura, S.
Regulation of Apoptosis Signal-regulating Kinase 1 by Protein Phosphatase 2Cε.
Biochem. J., 405, 591-596 (2007).
  Kani, S., Nakayama, E., Yoda, A., Onishi, N., Sougawa, N., Hazaka, Y., Umeda, T., Takeda, K., Ichijo, H., Hamada, Y. and Minami, Y.
Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling.
Genes Cells, 12, 919-928 (2007).
  Yamashita, T., Yamamoto, E., Kataoka, K., Nakamura, T., Matsuba, S., Tokutomi, Y., Dong, Y-F. Ichijo, H., Ogawa, H. and Kim-Mitsuyama, S.
Apoptosis Signal-regulating Kinase-1 is involved in vascular endothelial and cardiac remodeling caused by nitric oxide deficiency.
Hypertension, 50, 519-524 (2007).
  Galvan, V., Banwait, S., Spilman, P., Gorostiza, O.F., Peel, A., Ataie, M., Crippen, D., Huang, W., Sidhu, G., Ichijo, H. and Bredesen, D.E.
Interaction of ASK1 and the beta-amyloid precursor protein in a stress-signaling complex.
Neurobiol Dis., 28, 65-75 (2007).

Terada, Y., Inoshita, S., Kuwana, H., Kobayashi, T., Okado, T., Ichijo, H. and Sasaki, S.
Important role of apoptosis signal-regulating kinase 1 in ischemic acute kidney injury.
Biochem. Biophys. Res. Commun., 364, 1043-1049 (2007).
  Yamamoto, E., Kataoka, K., Shintaku, H., Yamashita, T., Tokutomi, Y., Dong, Y. F., Matsuba, S., Ichijo, H., Ogawa, H. and Kim-Mitsuyama, S.
Novel mechanism and role of angiotensin II-induced vascular endothelial injury in hypertensive diastolic heart failure.
Arterioscler. Thromb. Vasc. Biol., 27, 2569-2575 (2007).
  Yang, C.-S., Shin, D.-M., Lee, H.-M., Chang, M., Son, J. W., Lee, S. J., Akira, S., El-Benna, J., Ichijo, H. and Jo, E.-K.
ASK1-p38 MAPK-p47phox activation is essential for inflammatory responses during tuberculosis via TLR2-ROS signalling.
Cell. Microbiol., 10, 741-754 (2007).

Review articles

  Nagai, H., Noguchi, T., Takeda, K.and Ichijo, H. Pathophysiological Roles of ASK1-MAP Kinase Signaling Pathways.
J. Biochem. Mol. Biol., (review article), 40, 1-6 (2007).
  Murakami, S., Noguchi, T., Takeda, K. and Ichijo, H. Stress signaling in cancer.
Cancer Sci., (review article), 98, 1521-1527 (2007).
  Fujisawa, T., Takeda, K. and Ichijo, H. ASK family proteins in stress response and disease.
Mol. Biotechnol., (review article), 37, 13-18 (2007).