Sekine,Y., Takagahara,S., Hatanaka, R., Watanabe, T., Oguchi, H., Noguchi, T., Naguro, I., Kobayashi, K., Tsunoda, M., Funatsu, T., Nomura, H., Toyoda, T., Matsuki, N., Kuranaga, E., Miura, M., Takeda, K. and Ichijo,H.
p38 MAP kinase regulates the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors.
J. Cell Sci., 124, 3006-3016 (2011).
Hayakawa, T., Kato, K., Hayakawa, R., Hisamoto, N., Matsumoto, K., Takeda, K. and Ichijo, H.
Regulation of anoxic death in Caenorhabditis elegans by mammalian apoptosis signal-regulating kinase (ASK) family proteins
Genetics, 187, 785-792 (2011).
Dosal, R.G., Horan, K.A., Rahbek, S.H., Ichijo, H., Chen, Z.J., Mieyal, J.J., Hartmann, R., Paludan, S.R.
HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6.
PLoS Pathogens, e1002250 (2011).
Hayakawa, Y., Hirata, Y., Nakagawa, H., Sakamoto, K., Hikiba, Y., Kinoshita, H., Nakata, W., Takahashi, R., Tateishi, K., Tada, M., Akanuma, M., Yoshida, H., Takeda, K., Ichijo, H., Omata, M., Maeda, S., Koike, K.
Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer.
Proc. Natl. Acad. Sci. USA., 108, 780-785 (2011).
Nakagawa, H., Hirata, Y., Takeda, K., Hayakawa, Y., Sato, T., Kinoshita, H., Sakamoto, K., Nakata, W., Hikiba, Y., Omata, M., Yoshida, H., Koike, K. Ichijo, H. and Maeda, S.
Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated MAPK.
Hepatology, 54, 185-195 (2011).
Makena, P.S., Gorantla, V.K., Ghosh, M.C., Bezawada, L., Kandasamy, K., Balazs, L., Luellen, C.L., Thompson, K.E., Parthasarathi, K., Ichijo, H., Waters, C.M. and Sinclair, S.E.
Deletion of apoptosis signal regulating kinase-1 prevents ventilatorinduced lung injury in mice.
Am. J. Respir. Cell Mol. Biol., 46, 461-469 (2011).
Yamada, S., Ding, Y., Tanimoto, A., Wang, K.Y., Guo, X., Li, Z., Tasaki, T., Nabesima, A., Murata, Y., Shimajiri, S., Kohno, K., Ichijo, H. and Sasaguri, Y.
Apoptosis Signal-Regulating Kinase 1 Deficiency Accelerates Hyperlipidemia-Induced Atheromatous Plaques via Suppression of Macrophage Apoptosis.
Arterioscler. Thromb. Vasc. Biol., 31, 1555-1564 (2011).
Okamoto, M., Saito, N., Kojima, H., Okabe, T., Takeda, K., Ichijo, H., Furuya, T. and Nagano, T.
Identification of novel ASK1 inhibitors using virtual screening.
Bioorg. Med. Chem., 19, 486-489 (2011).
Review articles
Runchel, C., Matsuzawa, A. and Ichijo, H.
MAPKs in mammalian oxidative stress responses.
Antioxid. Redox Signal., (review article), 15, 205-218 (2011).
Takeda, K., Naguro, I., Nishitoh, H.,Matsuzawa, A. and Ichijo, H.
Apoptosis signaling kinases: from stress response to health outcomes.
Antioxid. Redox Signal., (review article), 15, 719-761 (2011).