Hirata, Y., Katagiri, K., Nagaoka, K., Morishita, T., Kudoh, Y., Hatta, T., Naguro, I., Kano, K., Udagawa, T., Natsume, T., Aoki, J., Inada, T., Noguchi, T., Ichijo, H. and Matsuzawa, A.
TRIM48 promotes ASK1 activation and cell death through ubiquitination-dependent degradation of the ASK1 negative regulator PRMT1.
Cell Rep., 21, 2447-2457 (2017).
Hattori, K., Ishikawa, H., Sakauchi, C., Takayanagi, S., Naguro, I. and Ichijo, H.
Cold stress-induced ferroptosis involves the ASK1-p38 pathway.
EMBO Rep., 18, 2067-2078 (2017).
Kamiyama, M., Shirai, T., Tamura, S., Suzuki-Inoue, K., Ehata, S., Takahashi, K., Miyazono, K., Hayakawa, Y., Sato, T., Takeda, K., Naguro, I. and Ichijo, H.
ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y12 in platelets.
Cell Death Differ., 24, 2066-2076 (2017).
Imamura, K., Izumi, Y., Watanabe, A., Tsukita, K., Woltjen, K., Yamamoto, T., Hotta, A., Kondo, T., Kitaoka, S., Ohta, A., Tanaka, A., Watanabe, D., Morita, M., Takuma, H., Tamaoka, A., Kunath, T., Wray, S., Furuya, H., Era, T., Makioka, K., Okamoto, K., Fujisawa, T., Nishitoh, H., Homma, K., Ichijo, H., Julien, J.-P., Obata, N., Hosokawa, M., Akiyama, H., Kaneko, S., Ayaki, T., Ito, H., Kaji, R., Takahashi, R., Yamanaka, S. and Inoue, H.
iPSC-based drug repositioning identifies the Src/c-Abl pathway as a therapeutic target for ALS motor neurons.
Sci. Transl. Med., 9, pii: eaaf3962 (2017).
Chaikuad,A., Chaikuad, A., Filippakopoulos, P., Marcsisin, S. R., Picaud, S., Sekine, S., Ichijo, H., Engen, J. R.,Takeda, K. and Knapp, S.
Structures of PGAM5 provide insight into active site dynamics and multimeric assembly.
Structure, 25, 1089-1099 (2017).
Maruoka, S., Gon, Y., Mizumura, K., Okamoto, S., Tsuya, K., Shikano, S., Soda, K., Naguro, I., Ichijo, H. and Hashimoto, S.
Involvement of apoptosis signal-regulating kinase-1 in house dust mite-induced allergic asthma in mice.
Allergol. Int., 66S, S50-S52 (2017).
Naik, M.-U. Patel, P., Derstine, R., Turaga, R., Chen, X., Golla, K., Neeves, K.-B., Ichijo, H. and Naik, U.-K.
Apoptosis signal-regulating kinase 1 regulates platelet granule secretion, thromboxane A2 generation, and thrombus formation in mice.
Blood, i29, 1197-1209 (2017).
Review articles
Ryuno, H., Naguro, I. and Kamiyama, M.
ASK family and cancer.
Adv. Biol. Regal., (review article), 66, 72-84 (2017).
Nishida, T., Hattori, K. and Watanabe, K.
The regulatory and signaling mechanisms of the ASK family.
Adv. Biol. Regul., (review article), 66, 2-22 (2017).
Sakauchi, C., Wakatsuki, H., Ichijo, H. and Hattori, K.
Pleiotropic properties of ASK1.
Biochem. Biophys. Acta., (review article), 1861, 3030-3038 (2017).
Fujisawa, T., Filippakopoulos, P.
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer.
Nat. Rev. Mol. Cell. Biol., (review article), 18, 246-262 (2017).
Fujisawa, T.* * corresponding author
Therapeutic application of apoptosis signal-regulating kinase 1 inhibitors.
Adv. Biol. Regul., (review article), 66, 85-90 (2017).