Ito-Kureha, T., Miyao, T., Nishijima, S., Suzuki, T., Koizumi, S., Villar-Briones, A., Takahashi, A., Akiyama, N., Morita, M., Naguro, I., Ishikawa, H., Ichijo, H., Akiyama, T. and Yamamoto, T.
The CCR4-NOT deadenylase complex safeguards thymic positive selection by down-regulating aberrant pro-apoptotic gene expression.
Nat. Commun., 11, 6169 (2020).
Hattori, K., Wakatsuki H., Sakauchi, C., Furutani, S., Sugawara, S., Hatta, T., Natsume, T. and Ichijo, H.
β-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes.
PLOS ONE, 15, e0232645 (2020).
Hattori, K., Wakatsuki H., Sakauchi, C., Furutani, S., Hatta, T., Natsume, T. and Ichijo, H.
β-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes.
bioRxiv 2020.04.21.052985 (2020).
Nakamura, R., Numata, T., Kasuya, G., Yokoyama, T., Nishizawa, T., Kusakizako, T., Kato, T., Hagino, T., Dohmae, N., Inoue, M., Watanabe, K., Ichijo, H., Kikkawa, M., Shirouzu, M., Jentsch, T.J., Ishitani, R., Okada, Y., Nureki, O.
Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation.
Commun. Biol., 3, 240 (2020).
Sugawara, S., Kanamaru, Y., Sekine, S., Maekawa, L., Takahashi, A., Yamamoto, T., Watanabe, K., Fujisawa, T., Hattori, K. and Ichijo, H.
The mitochondrial protein PGAM5 suppresses energy consumption in brown adipocytes by repressing expression of uncoupling protein 1.
J. Biol. Chem., 295, 5588-5601 (2020).
Homma, K., Takahashi, H., Tsuburaya, N., Naguro, I., Fujisawa, T. and Ichijo, H.
Genome-wide siRNA screening reveals that DCAF4-mediated ubiquitination of optineurin stimulates autophagic degradation of Cu/Zn superoxide dismutase.
J. Biol. Chem., 295, 3148-3158 (2020).
Yoshikawa, M., Iriyama, T., Suzuki, K., Sayama, S., Tsuruga, T., Kumasawa, K., Nagamatsu, T., H omma, K., Naguro, I., Osuga, Y., Ichijo, H. and Fujii, T. ASK1 promotes uterine inflammation leading to pathological preterm birth.
Sci. Rep., 10, 1887 (2020).
Kato, H., Okabe, K., Miyake, M., Hattori, K., Fukaya, T., Tanimoto, K., Beini, S., Mizuguchi, M., Torii, S., Arakawa, S., Ono, M., Saito, Y., Sugiyama, T., Funatsu, T., Sato, K., Shimizu, S., Oyadomari, S., Ichijo, H., Kadowaki, H. and Nishitoh, H.
ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.
Life Sci. Alliance, 3, pii: e201900576 (2020).
Review articles
Kojima, K., Ichijo, H. and Naguro, I.
Molecular functions of ASK family in diseases caused by stress-induced inflammation and apoptosis
J. Biochem., (review article), 169, 395-407, (2020).
Takenaka, S., Fujisawa, T., Ichijo, H.
Apoptosis signal-regulating kinase 1 (ASK1) as a therapeutic target for neurological diseases.
Expert Opin. Ther. Targets, (review article), 24, 1061-1064 (2020).