Watanabe, K., Morishita, K., Zhou, X., Shiizaki, S., Uchiyma, Y., Koike, M., Naguro, I. and Ichijo, H.
Cells recognize osmotic stress through liquid–liquid phase separation lubricated with poly(ADP-ribose).
Nat. Commun., 12,1353 (2021).

論文がEditor's Highlightsに選ばれました!
プレスリリースはこちら
Watanabe, K., Morishita, K., Zhou, X., Shiizaki, S., Uchiyma, Y., Koike, M., Naguro, I. and Ichijo, H.
Cells recognize osmotic stress through liquid–liquid phase separation lubricated with poly(ADP-ribose).
bioRxiv 2020.04.20.049759 (2020).

  Ogawa, M., Kawarazaki, Y., Fujita, Y., Naguro, I. and Ichijo, H.
FGF21 induced by the ASK1-p38 pathway promotes mechanical cell competition by attracting cells.
Curr. Biol., 31, 1-10 (2021).
論文がDispatchで紹介されました!
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  Takayanagi, S., Watanabe, K., Maruyama, T., Ogawa, M., Morishita, K., Soga, M., Hatta, T., Natsume, T., Hirano, T., Kagechika, H., Hattori, K., Naguro, I. and Ichijo, H.
ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes.
Sci. Rep., 11, 22009 (2021).

  Nakamura, T., Ogawa, M., Kojima, K., Takayanagi, S., Ishihara, S., Hattori, K., Naguro, I. and Ichijo, H.
The mitochondrial Ca2+ uptake regulator, MICU1 is involved in cold stress-induced ferroptosis.
EMBO Rep., 22, e51532 (2021).
プレスリリースはこちら

  Fujimoto, M., Kamiyama, M., Fuse, K., Ryuno, H., Odawara, T., Furukawa, N., Yoshimatsu, Y., Watabe, T., Michaela, P.-M. Veronika, S., Tahara, H., Hayakawa, Y., Sato, T., Takeda, K., Naguro, I. and Ichijo, H.
ASK1 suppresses NK cell-mediated intravascular tumor cell clearance in lung metastasis.
Cancer Sci., 112, 1633-1643 (2021).

   Sugiyama, T., Murao, N., Kadowaki, H., Takao, K., Miyakawa, T., Matsushita, Y., Katagiri, T., Futatsugi, A., Shinmyo, Y., Kawasaki, H., Sakai, J., Shiomi, K., Nakazato, M., Takeda, K., Mikoshiba, K., Ploegh, H.L., Ichijo, H. and Nishitoh, H.
ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function.
iScience, 24, 102758 (2021).

  Matsui, H., Iriyama, T., Sayama, S., Inaoka, N., Suzuki, K., Yoshikawa, M., Ichinose, M., Sone, K., Kumasawa, K., Nagamatsu, T., Fujisawa, T., Naguro, I., Ichijo, H., Fujii, T. and Osuga, Y.
Elevated placental histone H3K4 methylation via upregulated histone methyltransferases SETD1A and SMYD3 in preeclampsia and its possible involvement in hypoxia-induced pathophysiological process.
Placenta, 115, 60-69 (2021).

  Blasio, C. De, Verma, N., Moretti, M., Cialfi, S., Zonfrilli, A., Franchitto, M., Truglio, F., Smaele, E.De, Ichijo, H. Naguro, I., Screpaniti, I. and Talora, C.
Functional cooperation between ASK1 and p21Waf1/Cip1 in the balance of cell cycle arrest, cell death and tumorigenesis of stressed keratinocytes.
Cell Death Discov., 7, 75 (2021).

Review article

  Ishihara, S., Ichijo, H., Watanabe, K.
A novel lens for cell volume regulation: liquid–liquid phase separation.
Cell Physiol. Biochem., (review article), 55, 135-160 (2021).