業績目録
論文業績（英文）
- Naguro, I., Umeda, T., Kobayashi, Y., Maruyama, J., Hattori, K., Shimizu, Y., Kataoka, K., Kim-Mitsuyama, S., Uchida, S., Vandewalle, A., Noguchi, T., Nishitoh, H., Matsuzawa, A., Takeda, K. and Ichijo, H.
ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney.
Nat. Commun., doi: 10.1038/ncomms2283 (2012).
- Shiizaki, S., Naguro, I. and Ichijo, H.
Activation mechanisms of ASK1 in response to various stresses and its significance in intracellular signaling.
Adv. Biol. Regul., (review article), pii: S2212-4926(12)00090-5. doi: 10.1016/j.jbior.2012.09.006.
- Fujisawa, T., Homma, K., Yamaguchi, N., Kadowaki, H., Tsuburaya, N., Naguro, I., Matsuzawa, A., Takeda, K., Takahashi, Y., Goto, J., Tsuji, S., Nishitoh, H. and Ichijo, H.
A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants.
Ann. Neurol., 72, 739-749 (2012).
- Sekine,Y., Takagahara,S., Hatanaka, R., Watanabe, T., Oguchi, H., Noguchi, T., Naguro, I., Kobayashi, K., Tsunoda, M., Funatsu, T., Nomura, H., Toyoda, T., Matsuki, N., Kuranaga, E., Miura, M., Takeda, K. and Ichijo,H.
p38 MAP kinase regulates the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors.
J. Cell Sci. 124, 3006-3016 (2011).
- Takeda, K., Naguro, I., Nishitoh, H.,Matsuzawa, A. and Ichijo, H.
Apoptosis signaling kinases: from stress response to health outcomes.
Antioxid. Redox Signal. (review article), 15, 719-761 (2011).
- Maruyama, T., Kadowaki, H., Okamoto, N., Nagai, A., Naguro, I., Matsuzawa, A., Shibuya, H., Tanaka, K., Murata, S., Takeda, K., Nishitoh, H. and Ichijo, H.
CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.
EMBO J., 29, 2501-2514 (2010).
- Shimizu, Y., Naguro, I., Nishitoh, H. and Ichijo, H.
ER stress-induced cell death and inflammatory signaling: a therapeutic insight into intractable diseases.
Endoplasmic Reticulum Stress and Human Disease, (review article), in press.
- Hattori, K., Naguro, I., Runchel, C. and Ichijo, H.
The roles of ASK
family proteins in stress responses and diseases.
Cell Communication and Signaling, (review article), 7, 9 (2009).
- Maruyama, J., Naguro, I., Takeda, K. and Ichijo, H.
Stress-Activated MAP Kinase Cascades in Cellular Senescence.
Curr. Med. Chem., (review article), 16, 1229-1235 (2009).
- Iriyama, T., Takeda, K., Nakamura, H., Morimoto, Y., Kuroiwa, T., Mizukami, J., Umeda, T., Noguchi, T., Naguro, I., Nishitoh, H., Saegusa, K., Tobiume, K., Homma, T., Shimada, Y., Tsuda, H., Aiko, S., Imoto, I., Inazawa, J., Chida, K., Kamei, Y., Kozuma, S., Taketani, Y., Matsuzawa, A. and Ichijo, H.
ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.
EMBO J., 28, 843-853 (2009).
- Noguchi, T., Ishii, K., Fukutomi, H., Naguro, I., Matsuzawa, A., Takeda, K.
and Ichijo, H.
Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAP kinase pathway for extracelluler ATP-induced apoptosis in macrophage.
J. Biol. Chem., 283, 7657-7665 (2008).
- Takeda, K., Noguchi, T., Naguro, I. and Ichijo, H.
Apoptosis Signal-regulating Kinase 1 (ASK1) in stress and immune response.
Annu. Rev. Pharmacol. Toxicol., (review article), 48, 199-225 (2008).
- Takeda, K., Shimozono, R., Noguchi, T., Umeda, T., Morimoto, Y., Naguro, I., Tobiume, K., Saitoh, M., Matsuzawa, A. and Ichijo, H.
Apoptosis signal-regulating kinase 2 (ASK2) functions as a MAP3K in a heteromeric
complex with ASK1.
J. Biol. Chem., 282, 7522-7531 (2007).
- Yokoyama, U., Minamisawa, S., Adachi-Akahane, S., Akaike, T., Naguro, I., Funakoshi, K., Iwamoto, M., Nakagome, M., Uemura, N., Hori, H., Yokota, S. and Ishikawa, Y. Multiple transcripts of Ca2+ channel alpha1-subunit and a novel spliced variant of the alpha1C-subunit in rat ductus arteriosus.
Am. J. Physiol. Heart Circ. Physiol., 290, H1660-1670 (2006).
- Naguro, I., Adachi-Akahane, S. and Ichijo, H.
Calcium signaling via voltage-dependent L-type Ca2+ channels.
Signal Transduction (review article), 4, 195-205 (2004).
- Naguro, I., Nagao, T. and Adachi-Akahane, S. Ser(1901) of alpha(1C) subunit is required for the PKA-mediated enhancement of L-type Ca(2+) channel currents but not for the negative shift of activation.
FEBS Lett., 489, 87-91 (2001).
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